Eric T Choi Selected Research

Caspase 1 (ICE Protease)

11/2021	Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation.
1/2021	Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repair and Modulate Anti-Tumor Immunity via ROS Pathways.
1/2018	Uremic toxins are conditional danger- or homeostasis-associated molecular patterns.
10/2017	A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors.
1/2016	Caspase-1 mediates hyperlipidemia-weakened progenitor cell vessel repair.
4/2015	Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway.

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Eric T Choi Research Topics

Disease

14	Neoplasms (Cancer) 11/2021 - 02/2013
14	Inflammation (Inflammations) 11/2021 - 11/2012
10	Cardiovascular Diseases (Cardiovascular Disease) 11/2021 - 02/2013
8	Chronic Renal Insufficiency 01/2021 - 06/2009
6	Autoimmune Diseases (Autoimmune Disease) 11/2021 - 02/2013
5	Metabolic Diseases (Metabolic Disease) 01/2018 - 01/2013
4	Hyperlipidemias (Hyperlipidemia) 01/2021 - 04/2015
4	Atherosclerosis 04/2015 - 08/2003
4	Endoleak 10/2010 - 02/2003
4	Aneurysm (Aneurysms) 03/2007 - 05/2004
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2018 - 11/2016
3	Hyperplasia 04/2016 - 06/2007
2	Cytokine Release Syndrome 11/2021 - 01/2021
2	Diabetic Foot 05/2021 - 09/2018
2	Wounds and Injuries (Trauma) 01/2021 - 01/2019
2	Abdominal Aortic Aneurysm 01/2021 - 05/2004
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2020 - 11/2012
2	Insulin Resistance 01/2020 - 01/2018
2	Hyperhomocysteinemia 01/2017 - 11/2016
2	Myocardial Infarction 01/2017 - 01/2016
2	Ischemia 07/2015 - 02/2015
2	Fistula 01/2015 - 03/2010
2	Pathologic Constriction (Stenosis) 09/2014 - 07/2004
2	Arteriovenous Fistula 09/2014 - 03/2010
2	Atherosclerotic Plaque (Atheroma) 06/2007 - 05/2005
2	Neointima 06/2007 - 03/2004
1	Infections 11/2021
1	Peripheral Arterial Disease 05/2021
1	Ulcer 05/2021
1	Hypertension (High Blood Pressure) 01/2021
1	Coronavirus Infections 01/2021
1	Viremia 01/2021
1	COVID-19 01/2021
1	Thromboembolism 01/2021
1	Immune System Diseases (Immune Disorders) 01/2021
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020
1	Disease Progression 01/2020
1	Leukemia 01/2019
1	Chronic Disease (Chronic Diseases) 01/2019
1	Bacterial Infections (Bacterial Infection) 01/2019
1	Chondrosarcoma 01/2019
1	Hyperthermia 01/2019
1	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 01/2019
1	Hypoxia (Hypoxemia) 01/2018
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2018
1	Thrombosis (Thrombus) 01/2017
1	Prostatic Neoplasms (Prostate Cancer) 01/2017
1	Lung Neoplasms (Lung Cancer) 01/2017

Drug/Important Bio-Agent (IBA)

8	CytokinesIBA 01/2021 - 02/2013
6	EnzymesIBA 11/2021 - 07/2015
6	Caspase 1 (ICE Protease)IBA 11/2021 - 04/2015
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2012
5	InflammasomesIBA 01/2021 - 01/2013
5	Apolipoproteins E (ApoE)IBA 01/2020 - 05/2005
4	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 12/2014
3	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2018
3	CaspasesIBA 01/2021 - 04/2016
3	ApolipoproteinsIBA 12/2014 - 08/2003
2	LipidsIBA 11/2021 - 01/2019
2	AntioxidantsIBA 01/2021 - 01/2019
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 02/2013
2	Histones (Histone)IBA 01/2020 - 02/2016
2	ChromatinIBA 01/2019 - 11/2016
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 01/2017
2	Oxygen (Dioxygen)IBA 10/2017 - 01/2017
2	CD40 Ligand (CD40L)IBA 01/2017 - 11/2016
2	LigandsIBA 01/2013 - 11/2012
1	Membrane Proteins (Integral Membrane Proteins)IBA 11/2021
1	InterferonsIBA 11/2021
1	ChemokinesIBA 01/2021
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2021
1	Angiotensin IIIBA 01/2021
1	CEACAM1 ProteinIBA 01/2021
1	oxidized low density lipoproteinIBA 01/2021
1	Coronavirus ReceptorsIBA 01/2021
1	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	Uremic ToxinsIBA 01/2020
1	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 01/2019
1	Histocompatibility Antigens Class IIIBA 01/2018
1	Rosiglitazone (Avandia)FDA Link 01/2018
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2017
1	Immune Checkpoint ProteinsIBA 01/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017
1	Interleukin-18 (Interleukin 18)IBA 01/2017
1	S-Adenosylmethionine (Ademetionine)IBA 11/2016
1	S-AdenosylhomocysteineIBA 11/2016
1	HomocysteineIBA 11/2016

Therapy/Procedure

7	Therapeutics 11/2021 - 02/2013
4	Stents 10/2010 - 07/2004
3	Transplantation 11/2021 - 01/2021
3	Ligation 02/2015 - 03/2004
3	Renal Dialysis (Hemodialysis) 01/2015 - 11/2012
2	Surgical Amputation (Amputations) 05/2021 - 09/2018
2	Lasers (Laser) 02/2015 - 03/2010
1	Endovascular Procedures 05/2021
1	Organ Transplantation 01/2021
1	Transjugular Intrahepatic Portasystemic Shunt 01/2019
1	Limb Salvage 09/2018